Belly fat may release more of a protein that can cause a non-cancerous cell to turn into a cancerous one, new research has found.
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According to a Study:
- Obesity has been linked to several types of cancers including that of the breast, colon, prostate, uterus or kidney.
- But the new study indicated that just being overweight is not necessarily the best way to determine risk.
- Study suggests that body mass index, or BMI, may not be the best indicator.
- It’s abdominal obesity and, even more specifically, levels of a protein called fibroblast growth factor-2.
- In addition,that may be a better indicator of the risk of cells becoming cancerous.
- There are two layers of belly fat.
- The top layer, known as subcutaneous fat, lies right under the skin.
- The layer under that, called visceral fat, is the one she found to be more harmful.
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Experiment:
- Studied mice that were fed a high-fat diet and discovered.
- That this higher-risk layer of fat produced larger amounts of the fibroblast growth factor-2, or FGF2, protein.
- Furthermore,when compared to the subcutaneous fat.
- They found that FGF2 stimulated certain cells that were already vulnerable to the protein.
- And caused them to grow into tumours.
- Also collected visceral fat tissue from women undergoing hysterectomies.
- And found that when the fat secretions had more of the FGF2 protein,
- More of the cells formed cancerous tumours when transferred into mice.
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- “This would indicate that fat from both mice and humans can make a non-tumorigenic cell malignantly transform into a tumorigenic cell,” Expert said.
- There are several other factors released from fat, including the hormone estrogen.
- That could influence cancer risk, but many of those studies have only been able to show an association and not a direct cause of cancer, Expert added.
- Genetics too play a role.
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