Turning conventional wisdom on its head, researchers including one of Indian-origin, have found that the excessive burst of new brain cells after a traumatic head injury. That scientists have traditionally believed helped in recovery could instead lead to epileptic seizures and long-term cognitive decline.

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Findings:

  • The findings suggest that memory decline after head injury may be prevented by slowing brain cell growth.
  • There is an initial increase in birth of new neurons after a brain injury but within weeks.
  • In addition,there is a dramatic decrease in the normal rate at which neurons are born.
  • Depleting brain cells that under normal circumstances should be there to replace damaged cells and repair the brain’s network.
  • “The excess new neurons lead to epileptic seizures and could contribute to cognitive decline,”Expert added.
  • Symptoms of traumatic brain injury can include impaired thinking or memory.
  • In addition,personality changes and depression and vision and hearing problems as well as epilepsy.
  • About 80 percent of those who develop epilepsy after a brain injury have seizures within the first two years after the damage occurs.

Experiments:

  • Studying laboratory rats, the scientists found that within a month after experimental brain injury.
  • In addition,the number of new brain cells declined dramatically.
  • Below the numbers of new neurons that would have detected if an injury had not occurred.
  • When scientists were able to prevent the excessive neurogenesis.
  • In addition,which occurs within days of the injury with a drug similar to one under trial for chemotherapy treatments.
  • The rate of birth of new brain cells went back to normal levels and risk for seizures was reduced.
  • “That’s why we believe that limiting this process might be beneficial to stopping seizures after brain injury,” Expert said.
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